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Українські рефератиРусские рефератыКниги
НазваDpt adsorbed (реферат)
РозділІноземна мова, реферати англійською, німецькою
ФорматWord Doc
Тип документуРеферат
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Реферат на тему:


Dpt adsorbed


Diphtheria and Tetanus Toxoids and Pertussis Vaccine


Adsorbed. For Active Immunization against Diphtheria,


Tetanus and Whooping Cough.


Description. Diphtheria and Tetanus Toxoids and Pertussis Vaccine

Adsorbed (DPT Vaccine Adsorbed) as supplied by Connaught Laboratories

Limited, is sterile, cloudy, uniform suspension of diphtheria and

tetanus toxoids and pertussis vaccine adsorbed on aluminium phosphate

and suspended in isotonic sodium chloride solution.


This vaccine fulfils the WHO requirements Diphtheria Toxoid, Tetanus

Toxoid and Pertussis Vaccine.


Indications. DPT Vaccine Adsorbed is indicated for the primary

immunization of infants at or above the age of two months, and of

children through 6 years of age against diphtheria, tetanus and whooping



Contraindications. DPT Vaccine Adsorbed should not be administered to

infants or children with fever, or other evidence of acute illness or

infection. The presence of an evolving or changing neurologic disorder

is a contraindication to receipt of this vaccine. A second or third DPT

injection should not be given to a child who has suffered a severe

adverse reaction to the previous dose. The pertussis component should be

omitted and diphtheria and tetanus immunization completed.


Elective immunization of individuals over б months of age should be

deferred during an outbreak of poliomyelitis.


DPT Vaccine Adsorbed should not be administered to children over б years

of age or to adults because of the danger of reactions to diphtheria

toxoid or to pertussis vaccine and because pertussis is less severe in

these age groups than in infants and young children.


Dosage. For primary immunization of infants and pre-school children

through 6 years of age, it is recommended that three intramuscular

injections of 0.5 ml be administered with an interval of four to eight

weeks between doses. For a lasting immunization effect, a fourth

injection of 0.5 ml is essential approximately one year following the

third dose.


Administration. The vaccine should be administered by intramuscular

injection. The musculus vastus lateralis (mid-thigh laterally) is the

preferred injection site for infants. The site of injection shoud be

prepared with a suitable antiseptic. Do not inject intravenously. Each

injection of the primary immunization series should be made into a

different area (site). If sterile disposable syringes and needles are

not used, syringes and needles should be sterilized in an autoclave at

121°С for 30 minutes. Failing that, they should be boiled for at least

20 minutes. Care should be taken to maintain sterility until used.


Storage. Diphtheria and Tetanus Toxoids and Pertussis Vaccine Adsorbed

shouls be stored and transported at a temperature between 2° and 8°C

(35° and 46°F). Do not freeze. Product which has been exposed to

freezing should not be used. When using a multi-dose vial, it is

recommended that partially used vials be discarded at the end of the



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