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НазваGastritis (гастрит) (реферат)
РозділІноземна мова, реферати англійською, німецькою
ФорматWord Doc
Тип документуРеферат
Замовити оригінальну роботу
Gastritis (гастрит)



1 Causes and Treatment 

1.1 Acute

1.2 Chronic 

1.2.1 Metaplasia

1.2.2 Helicobacter pylori

1.3 Treatment

2 Symptoms

3 Diagnosis

4 References

5 See also


Gastritis is an inflammation of the lining of the stomach, and has many
possible causes.[1] The main acute causes are excessive alcohol
consumption or prolonged use of nonsteroidal anti-inflammatory drugs
(also known as NSAIDs) such as aspirin or ibuprofen. Sometimes gastritis
develops after major surgery, traumatic injury, burns, or severe
infections. Gastritis may also occur in those who have had weight loss
surgery resulting in the banding or reconstruction of the digestive
tract. Chronic causes are infection with bacteria, primarily
Helicobacter pylori. Certain diseases, such as pernicious anemia,
chronic bile reflux, and certain autoimmune disorders can cause
gastritis as well. The most common symptom is abdominal upset or pain.
Other symptoms are indigestion, abdominal bloating, nausea, and
vomiting. Some may have a feeling of fullness or burning in the upper
abdomen.[2][3] A gastroscopy, blood test, complete blood count test, or
a stool test may be used to diagnose gastritis.[4] Treatment includes
taking antacids or other medicines, such as proton pump inhibitors or
antibiotics, or avoiding hot or spicy foods. For those with pernicious
anemia, B12 injections are given.[5]


Erosive gastritis is gastric mucosal erosion caused by damage to mucosal
defenses.[2] Alcohol consumption does not cause chronic gastritis. It
does, however, erode the mucosal lining of the stomach; low doses of
alcohol stimulate hydrochloric acid secretion. High doses of alcohol do
not stimulate secretion of acid.[6] NSAIDs inhibit cyclooxygenase-1, or
COX-1, an enzyme responsible for the biosynthesis of eicosanoids in the
stomach, which increases the possibility of peptic ulcers to form.[7]
Also, NSAIDs, such as aspirin, reduce a substance that protects the
stomach called prostaglandin. These drugs used in a short period of time
are not typically dangerous. However, regular use can lead to


If the cardiac sphincter fails to do its job properly, some stomach acid
can escape up the esophagus. This causes very painful "heartburn" or
"gastritis" in the chest as the esophageal walls are eroded by the
hydrochloric acid. Chronic gastritis refers to a wide range of problems
of the gastric tissues that are mainly the result of H. pylori
infection.[2] The immune system makes proteins and antibodies that fight
infections in the body to maintain a homeostatic condition. In some
disorders, the body accidentally targets the stomach, believing it is a
foreign protein or pathogen. It makes antibodies against, severely
damages, and may even destroy the stomach and/or its lining.[8] In some
cases, bile, normally used to aid digestion in the small intestine, will
enter through the pyloric valve of the stomach, because it had been
removed during surgery or may not work properly. This also leads to
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